EMD-11981
SARS-CoV-spike bound to two neutralising nanobodies
EMD-11981
Single-particle2.62 Å
Deposition: 24/11/2020Map released: 28/04/2021
Last modified: 28/04/2021
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Lama glama,
Vicugna pacos
Sample: SARS-CoV-2 glycoprotein in complex with two nanobodys named V
Fitted models: 7b18
Deposition Authors: Hallberg BM, Das H
Sample: SARS-CoV-2 glycoprotein in complex with two nanobodys named V
Fitted models: 7b18
Deposition Authors: Hallberg BM, Das H
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Koenig PA 
,
Das H ,
Liu H ,
Kummerer BM ,
Gohr FN ,
Jenster LM ,
Schiffelers LDJ ,
Tesfamariam YM ,
Uchima M ,
Wuerth JD ,
Gatterdam K ,
Ruetalo N,
Christensen MH ,
Fandrey CI ,
Normann S,
Todtmann JMP ,
Pritzl S,
Hanke L ,
Boos J ,
Yuan M ,
Zhu X ,
Schmid-Burgk JL ,
Kato H,
Schindler M ,
Wilson IA ,
Geyer M ,
Ludwig KU ,
Hallberg BM ,
Wu NC ,
Schmidt FI
(2021) Science , 371
,
Das H ,
Liu H ,
Kummerer BM ,
Gohr FN ,
Jenster LM ,
Schiffelers LDJ ,
Tesfamariam YM ,
Uchima M ,
Wuerth JD ,
Gatterdam K ,
Ruetalo N,
Christensen MH ,
Fandrey CI ,
Normann S,
Todtmann JMP ,
Pritzl S,
Hanke L ,
Boos J ,
Yuan M ,
Zhu X ,
Schmid-Burgk JL ,
Kato H,
Schindler M ,
Wilson IA ,
Geyer M ,
Ludwig KU ,
Hallberg BM ,
Wu NC ,
Schmidt FI
(2021) Science , 371