EMD-11951

Single-particle
2.877 Å
EMD-11951
3D View Gallery
Deposition: 17/11/2020
Map released: 19/05/2021
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11951

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7azy summary report (pdf.gz) Map-7azy FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Context-specific inhibition of eukaryotic translation by macrolide antibiotics

EMD-11951

Single-particle
2.877 Å
EMD-11951
3D View Gallery
Deposition: 17/11/2020
Map released: 19/05/2021
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sample: 60S ribosomal subunit with 25S rRNA mutation G2400A and telithromycin bound in the nascent peptide exit tunnel
Fitted models: 7azy

Deposition Authors: Koller TO , Wilson DN
Context-specific action of macrolide antibiotics on the eukaryotic ribosome.
Svetlov MS , Koller TO , Meydan S, Shankar V , Klepacki D, Polacek N , Guydosh NR , Vazquez-Laslop N , Wilson DN , Mankin AS
(2021) Nat Commun , 12 , 2803 - 2803
PUBMED: 33990576
DOI: doi:10.1038/s41467-021-23068-1
ISSN: 2041-1723
Grant Support: