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EMD-11927
Melanocortin receptor 4 (MC4R) Gs protein complex
EMD-11927
Single-particle2.97 Å
Deposition: 02/11/2020Map released: 28/04/2021
Last modified: 15/03/2023
Sample Organism:
Homo sapiens,
Mus musculus,
synthetic construct
Sample: Melanocortine 4 (MC4R) - GalphaS protein comlex
Fitted models: 7aue
Deposition Authors: Degtjarik O
,
Israeli H ,
Prabahar V ,
Shalev-Benami M
Sample: Melanocortine 4 (MC4R) - GalphaS protein comlex
Fitted models: 7aue
Deposition Authors: Degtjarik O
,
Israeli H ,
Prabahar V ,
Shalev-Benami M
Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling.
Israeli H ,
Degtjarik O ,
Fierro F ,
Chunilal V ,
Gill AK ,
Roth NJ,
Botta J ,
Prabahar V ,
Peleg Y ,
Chan LF ,
Ben-Zvi D ,
McCormick PJ ,
Niv MY ,
Shalev-Benami M
(2021) Science , 372 , 808 - 814
,
Degtjarik O ,
Fierro F ,
Chunilal V ,
Gill AK ,
Roth NJ,
Botta J ,
Prabahar V ,
Peleg Y ,
Chan LF ,
Ben-Zvi D ,
McCormick PJ ,
Niv MY ,
Shalev-Benami M
(2021) Science , 372 , 808 - 814