EMD-11822

Single-particle
3.5 Å
EMD-11822
3D View Gallery
Deposition: 09/10/2020
Map released: 13/01/2021
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11822

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7aml summary report (pdf.gz) Map-7aml FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

RET/GDNF/GFRa1 extracellular complex Cryo-EM structure

EMD-11822

Single-particle
3.5 Å
EMD-11822
3D View Gallery
Deposition: 09/10/2020
Map released: 13/01/2021
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Danio rerio
Sample: Ternary complex of RET extracellular domain with GDNF and GFRa1 ligand-coreceptor pair
Fitted models: 7aml

Deposition Authors: Adams SE, Earl CP
A two-site flexible clamp mechanism for RET-GDNF-GFR alpha 1 assembly reveals both conformational adaptation and strict geometric spacing.
Adams SE, Purkiss AG , Knowles PP, Nans A, Briggs DC , Borg A, Earl CP , Goodman KM, Nawrotek A, Borg AJ, McIntosh PB, Houghton FM , Kjaer S, McDonald NQ
(2021) Structure , 29 , 694
PUBMED: 33484636
DOI: doi:10.1016/j.str.2020.12.012
ISSN: 0969-2126
ASTM: STRUE6
Grant Support: