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EMD-11679

Single-particle
3.5 Å
EMD-11679
3D View Gallery
Deposition: 30/08/2020
Map released: 30/12/2020
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11679
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7a8p summary report (pdf.gz) Map and 7a8p FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.

EMD-11679

Single-particle
3.5 Å
EMD-11679
3D View Gallery
Deposition: 30/08/2020
Map released: 30/12/2020
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human POLRMT (lacking residues 1-104) in complex with IMT inhibitor.
Fitted models: 7a8p

Deposition Authors: Hillen HS , Bonekamp N
Small-molecule inhibitors of human mitochondrial DNA transcription.
Bonekamp NA , Peter B , Hillen HS , Felser A , Bergbrede T , Choidas A , Horn M , Unger A , Di Lucrezia R , Atanassov I , Li X , Koch U , Menninger S , Boros J , Habenberger P , Giavalisco P, Cramer P , Denzel MS, Nussbaumer P , Klebl B, Falkenberg M , Gustafsson CM , Larsson NG
(2020) Nature , 588 , 712 - 716
PUBMED: 33328633
DOI: doi:10.1038/s41586-020-03048-z
ISSN: 1476-4687
ASTM: NATUAS