EMD-11552

Single-particle
7.6 Å
EMD-11552
3D View Gallery
Deposition: 30/07/2020
Map released: 26/05/2021
Last modified: 02/06/2021
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11552

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Entire Human Top2a - Interface between ATPase and DNA-binding/cleavage domains

EMD-11552

Single-particle
7.6 Å
EMD-11552
3D View Gallery
Deposition: 30/07/2020
Map released: 26/05/2021
Last modified: 02/06/2021
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Etoposide-bound Entire Human Top2a

Deposition Authors: Vanden Broeck A, Lamour V
Structural basis for allosteric regulation of Human Topoisomerase II alpha.
Vanden Broeck A , Lotz C , Drillien R, Haas L , Bedez C, Lamour V
(2021) Nat Commun , 12 , 2962 - 2962
PUBMED: 34016969
DOI: doi:10.1038/s41467-021-23136-6
ISSN: 2041-1723