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EMD-11551

Single-particle
4.1 Å
EMD-11551
3D View Gallery
Deposition: 30/07/2020
Map released: 26/05/2021
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11551
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6zy6 summary report (pdf.gz) Map and 6zy6 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the Human topoisomerase II alpha DNA-binding/cleavage domain in State 2

EMD-11551

Single-particle
4.1 Å
EMD-11551
3D View Gallery
Deposition: 30/07/2020
Map released: 26/05/2021
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Etoposide-bound Human Top2a DNA-binding/cleavage domain in state 2
Fitted models: 6zy6

Deposition Authors: Vanden Broeck A , Lamour V
Structural basis for allosteric regulation of Human Topoisomerase II alpha.
Vanden Broeck A , Lotz C , Drillien R, Haas L , Bedez C, Lamour V
(2021) Nat Commun , 12 , 2962 - 2962
PUBMED: 34016969
DOI: doi:10.1038/s41467-021-23136-6
ISSN: 2041-1723