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EMD-11331
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Locked State
EMD-11331
Single-particle3.5 Å
Deposition: 08/07/2020Map released: 22/07/2020
Last modified: 16/10/2024
Sample Organism:
Severe acute respiratory syndrome coronavirus 2
Sample: Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer
Fitted models: 6zoz
Deposition Authors: Qu K
,
Xiong X
,
Scheres SHW
,
Briggs JAG
Sample: Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer
Fitted models: 6zoz
Deposition Authors: Qu K
,
Xiong X
,
Scheres SHW
,
Briggs JAG
A thermostable, closed SARS-CoV-2 spike protein trimer.
Xiong X
,
Qu K
,
Ciazynska KA
,
Hosmillo M,
Carter AP
,
Ebrahimi S,
Ke Z
,
Scheres SHW
,
Bergamaschi L,
Grice GL,
Zhang Y,
Nathan JA
,
Baker S,
James LC
,
Baxendale HE,
Goodfellow I,
Doffinger R
,
Briggs JAG
(2020) Nat Struct Mol Biol , 27 , 934 - 941
,
Qu K
,
Ciazynska KA
,
Hosmillo M,
Carter AP
,
Ebrahimi S,
Ke Z
,
Scheres SHW
,
Bergamaschi L,
Grice GL,
Zhang Y,
Nathan JA
,
Baker S,
James LC
,
Baxendale HE,
Goodfellow I,
Doffinger R
,
Briggs JAG
(2020) Nat Struct Mol Biol , 27 , 934 - 941
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UP_1201/16 (United Kingdom)
- European Research Council (ERC): ERC-CoG-648432 (United Kingdom)
- German Research Foundation (DFG): 240245660 - SFB1129 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_UP_A025_1013 (United Kingdom)
