EMD-11329
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x2 disulphide-bond mutant, G413C, V987C, single Arg S1/S2 cleavage site)
EMD-11329
Single-particle3.0 Å
Deposition: 08/07/2020Map released: 22/07/2020
Last modified: 16/10/2024
Sample Organism:
Severe acute respiratory syndrome coronavirus 2
Sample: Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer
Fitted models: 6zox
Deposition Authors: Qu K
,
Xiong X ,
Scheres SHW ,
Briggs JAG
Sample: Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer
Fitted models: 6zox
Deposition Authors: Qu K
,
Xiong X ,
Scheres SHW ,
Briggs JAG
A thermostable, closed SARS-CoV-2 spike protein trimer.
Xiong X ,
Qu K ,
Ciazynska KA ,
Hosmillo M,
Carter AP ,
Ebrahimi S,
Ke Z ,
Scheres SHW ,
Bergamaschi L,
Grice GL,
Zhang Y,
Nathan JA ,
Baker S,
James LC ,
Baxendale HE,
Goodfellow I,
Doffinger R ,
Briggs JAG
(2020) Nat Struct Mol Biol , 27 , 934 - 941
,
Qu K ,
Ciazynska KA ,
Hosmillo M,
Carter AP ,
Ebrahimi S,
Ke Z ,
Scheres SHW ,
Bergamaschi L,
Grice GL,
Zhang Y,
Nathan JA ,
Baker S,
James LC ,
Baxendale HE,
Goodfellow I,
Doffinger R ,
Briggs JAG
(2020) Nat Struct Mol Biol , 27 , 934 - 941
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UP_1201/16 (United Kingdom)
- European Research Council (ERC): ERC-CoG-648432 (European Union)
- German Research Foundation (DFG): 240245660 - SFB1129 (Germany)
- Medical Research Council (MRC, United Kingdom): MC_UP_A025_1013 (United Kingdom)