EMD-11309

Single-particle
4.3 Å
EMD-11309
3D View Gallery
Deposition: 06/07/2020
Map released: 08/12/2021
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11309

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6zn2 summary report (pdf.gz) Map-6zn2 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Partial structure of tyrosine hydroxylase in complex with dopamine showing the catalytic domain and an alpha-helix from the regulatory domain involved in dopamine binding.

EMD-11309

Single-particle
4.3 Å
EMD-11309
3D View Gallery
Deposition: 06/07/2020
Map released: 08/12/2021
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Tyrosine Hydroxylase
Fitted models: 6zn2

Deposition Authors: Bueno-Carrasco MT , Cuellar J
Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation.
Bueno-Carrasco MT , Cuellar J , Flydal MI , Santiago C , Krakenes TA , Kleppe R, Lopez-Blanco JR , Marcilla M , Teigen K , Alvira S , Chacon P , Martinez A , Valpuesta JM
(2022) Nat Commun , 13 , 74 - 74
PUBMED: 35013193
DOI: doi:10.1038/s41467-021-27657-y
ISSN: 2041-1723