EMD-11221
Cryo-EM structure of the regulatory linker of ALC1 bound to the nucleosome's acidic patch: hexasome class.
EMD-11221
Single-particle3.0 Å
Deposition: 24/06/2020Map released: 23/12/2020
Last modified: 10/07/2024
Sample Organism:
Xenopus laevis,
synthetic construct,
Homo sapiens
Sample: A hexasome (nucleosome lacking one of the two H2A-H2B dimers) with its acidic patch bound by the ALC1 linker regulatory region.
Fitted models: 6zhy
Deposition Authors: Bacic L
,
Gaullier G ,
Deindl S
Sample: A hexasome (nucleosome lacking one of the two H2A-H2B dimers) with its acidic patch bound by the ALC1 linker regulatory region.
Fitted models: 6zhy
Deposition Authors: Bacic L
,
Gaullier G ,
Deindl S
Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Lehmann LC ,
Bacic L ,
Hewitt G ,
Brackmann K,
Sabantsev A,
Gaullier G ,
Pytharopoulou S,
Degliesposti G ,
Okkenhaug H ,
Tan S,
Costa A,
Skehel JM,
Boulton SJ ,
Deindl S
(2020) Cell Rep , 33 , 108529 - 108529
,
Bacic L ,
Hewitt G ,
Brackmann K,
Sabantsev A,
Gaullier G ,
Pytharopoulou S,
Degliesposti G ,
Okkenhaug H ,
Tan S,
Costa A,
Skehel JM,
Boulton SJ ,
Deindl S
(2020) Cell Rep , 33 , 108529 - 108529
Secondary citations:
- Goddard TD, Huang CC, Meng EC, Pettersen EF, Couch GS, Morris JH & Ferrin TE. (2018) UCSF ChimeraX: Meeting Modern Challenges in Visualization and Analysis. Protein Sci, 27, 14 - 25
- & Croll TI. (2018) ISOLDE: a physically realistic environment for model building into low-resolution electron-density maps. Acta Crystallogr D Struct Biol, 74, 519 - 530
- Zivanov J, Nakane T & Scheres SHW. (2020) Estimation of high-order aberrations and anisotropic magnification from cryo-EM data sets in. IUCrJ, 7, 253 - 267
- & Scheres SH. (2012) RELION: implementation of a Bayesian approach to cryo-EM structure determination. J Struct Biol, 180, 519 - 530
Grant Support: