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EMD-11173
Association of three complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab
EMD-11173
Single-particle4.7 Å
Deposition: 14/06/2020Map released: 29/07/2020
Last modified: 02/07/2025
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: Complex of SARS-CoV-2 Spike ectodomain with EY6A Fab
Fitted models: 6zdg
Deposition Authors: Duyvesteyn HME
,
Zhou D ,
Zhao Y ,
Fry EE ,
Ren J ,
Stuart DI
Sample: Complex of SARS-CoV-2 Spike ectodomain with EY6A Fab
Fitted models: 6zdg
Deposition Authors: Duyvesteyn HME
,
Zhou D ,
Zhao Y ,
Fry EE ,
Ren J ,
Stuart DI
Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Zhou D ,
Duyvesteyn HME ,
Chen CP,
Huang CG,
Chen TH,
Shih SR ,
Lin YC,
Cheng CY,
Cheng SH,
Huang YC,
Lin TY,
Ma C ,
Huo J,
Carrique L ,
Malinauskas T ,
Ruza RR ,
Shah PNM ,
Tan TK ,
Rijal P ,
Donat RF ,
Godwin K,
Buttigieg KR,
Tree JA ,
Radecke J,
Paterson NG ,
Supasa P,
Mongkolsapaya J,
Screaton GR ,
Carroll MW,
Gilbert-Jaramillo J ,
Knight ML ,
James W ,
Owens RJ ,
Naismith JH,
Townsend AR,
Fry EE ,
Zhao Y ,
Ren J ,
Stuart DI ,
Huang KA
(2020) Nat Struct Mol Biol , 27 , 950 - 958
,
Duyvesteyn HME ,
Chen CP,
Huang CG,
Chen TH,
Shih SR ,
Lin YC,
Cheng CY,
Cheng SH,
Huang YC,
Lin TY,
Ma C ,
Huo J,
Carrique L ,
Malinauskas T ,
Ruza RR ,
Shah PNM ,
Tan TK ,
Rijal P ,
Donat RF ,
Godwin K,
Buttigieg KR,
Tree JA ,
Radecke J,
Paterson NG ,
Supasa P,
Mongkolsapaya J,
Screaton GR ,
Carroll MW,
Gilbert-Jaramillo J ,
Knight ML ,
James W ,
Owens RJ ,
Naismith JH,
Townsend AR,
Fry EE ,
Zhao Y ,
Ren J ,
Stuart DI ,
Huang KA
(2020) Nat Struct Mol Biol , 27 , 950 - 958
Grant Support:
- Medical Research Council (MRC, United Kingdom): MR/N00065X/1 (United Kingdom)
- Wellcome Trust: 101122/Z/13/Z (United Kingdom)
- CAMS Innovation Fund for Medical Sciences (CIFMS): 2018-I2M-2-002 (China)