EMD-11068
Cryo-EM Structure of SARS-CoV-2 Spike : H11-D4 Nanobody Complex
EMD-11068
Single-particle3.3 Å
Deposition: 22/05/2020Map released: 03/06/2020
Last modified: 16/10/2024
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Lama glama
Sample: Spike glycoprotein in complex with H11-D4 nanobodies
Fitted models: 6z43
Deposition Authors: Ruza RR
,
Duyvesteyn HME
Sample: Spike glycoprotein in complex with H11-D4 nanobodies
Fitted models: 6z43
Deposition Authors: Ruza RR
,
Duyvesteyn HME
Structural basis for a potent neutralising single-domain antibody that blocks SARS-CoV-2 binding to its receptor ACE2
Huo J ,
Le Bas A ,
Ruza RR ,
Duyvesteyn HME ,
Mikolajek H ,
Malinauskas T ,
Tan T,
Rijal P ,
Dumoux M ,
Ward PN ,
Ren J ,
Zhou D ,
Harrison PJ ,
Radecke J ,
Zhao Y ,
Jaramillo JG,
Knight M,
Carrique L ,
Shah P,
James W ,
Townsend A,
Stuart DI ,
Owens RJ ,
Naismith JH
To Be Published
,
Le Bas A ,
Ruza RR ,
Duyvesteyn HME ,
Mikolajek H ,
Malinauskas T ,
Tan T,
Rijal P ,
Dumoux M ,
Ward PN ,
Ren J ,
Zhou D ,
Harrison PJ ,
Radecke J ,
Zhao Y ,
Jaramillo JG,
Knight M,
Carrique L ,
Shah P,
James W ,
Townsend A,
Stuart DI ,
Owens RJ ,
Naismith JH
To Be Published
Grant Support:
- Engineering and Physical Sciences Research Council: EP/S025243/1 (United Kingdom)
- Wellcome Trust: 100209/Z/12/Z (United Kingdom)
- Cancer Research UK: C20724/A14414 (United Kingdom)
- Cancer Research UK: C20724/A26752 (United Kingdom)
- Wellcome Trust: 101122/Z/13/Z (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MR/N00065X/1 (United Kingdom)