Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-11051

Single-particle
3.2 Å
EMD-11051 Deposition: 18/05/2020
Map released: 11/11/2020
Last modified: 22/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11051

Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP (State II)

EMD-11051

Single-particle
3.2 Å
EMD-11051 Deposition: 18/05/2020
Map released: 11/11/2020
Last modified: 22/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae S288C
Sample: Mec1-Ddc2
Fitted models: 6z2x

Deposition Authors: Yates LA , Zhang X
Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase.
Tannous EA, Yates LA , Zhang X , Burgers PM
(2021) Nat Struct Mol Biol , 28 , 50 - 61
PUBMED: 33169019
DOI: doi:10.1038/s41594-020-00522-0
ISSN: 1545-9985
Grant Support: