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EMD-10705
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
EMD-10705
Single-particle2.86 Å
Deposition: 26/02/2020Map released: 01/07/2020
Last modified: 16/10/2024
Sample Organism:
Escherichia coli (strain K12)
Sample: Cryo-EM structure of the antibiotic TetracenomycinX bound to the Escherichia coli 70S ribosome
Fitted models: 6y69
Deposition Authors: Wieland M
,
Wilson DN
Sample: Cryo-EM structure of the antibiotic TetracenomycinX bound to the Escherichia coli 70S ribosome
Fitted models: 6y69
Deposition Authors: Wieland M
,
Wilson DN
Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Osterman IA ,
Wieland M ,
Maviza TP ,
Lashkevich KA ,
Lukianov DA ,
Komarova ES ,
Zakalyukina YV ,
Buschauer R ,
Shiriaev DI ,
Leyn SA ,
Zlamal JE,
Biryukov MV ,
Skvortsov DA,
Tashlitsky VN ,
Polshakov VI ,
Cheng J ,
Polikanov YS ,
Bogdanov AA,
Osterman AL,
Dmitriev SE ,
Beckmann R,
Dontsova OA,
Wilson DN ,
Sergiev PV
(2020) Nat Chem Biol , 16 , 1071 - 1077
,
Wieland M ,
Maviza TP ,
Lashkevich KA ,
Lukianov DA ,
Komarova ES ,
Zakalyukina YV ,
Buschauer R ,
Shiriaev DI ,
Leyn SA ,
Zlamal JE,
Biryukov MV ,
Skvortsov DA,
Tashlitsky VN ,
Polshakov VI ,
Cheng J ,
Polikanov YS ,
Bogdanov AA,
Osterman AL,
Dmitriev SE ,
Beckmann R,
Dontsova OA,
Wilson DN ,
Sergiev PV
(2020) Nat Chem Biol , 16 , 1071 - 1077
Grant Support:
- German Research Foundation (DFG): WI3285/6-1 (Germany)