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EMD-10695

Single-particle
3.15 Å
EMD-10695
3D View Gallery
Deposition: 25/02/2020
Map released: 23/09/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-10695
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6y5e summary report (pdf.gz) Map and 6y5e FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of human cGAS (K394E) bound to the nucleosome (focused refinement of cGAS-NCP subcomplex)

EMD-10695

Single-particle
3.15 Å
EMD-10695
3D View Gallery
Deposition: 25/02/2020
Map released: 23/09/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo EM structure of cGAS-NCP1 complex
Fitted models: 6y5e

Deposition Authors: Pathare GR , Cavadini S
Structural mechanism of cGAS inhibition by the nucleosome.
Pathare GR , Decout A , Gluck S , Cavadini S, Makasheva K , Hovius R , Kempf G, Weiss J , Kozicka Z , Guey B , Melenec P , Fierz B , Thoma NH , Ablasser A
(2020) Nature , 587 , 668 - 672
PUBMED: 32911482
DOI: doi:10.1038/s41586-020-2750-6
ISSN: 1476-4687
ASTM: NATUAS