EMD-10694

Single-particle
4.1 Å
EMD-10694
3D View Gallery
Deposition: 25/02/2020
Map released: 23/09/2020
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-10694

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6y5d summary report (pdf.gz) Map-6y5d FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of human cGAS (K394E) bound to the nucleosome

EMD-10694

Single-particle
4.1 Å
EMD-10694
3D View Gallery
Deposition: 25/02/2020
Map released: 23/09/2020
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of cGAS-NCP complex
Fitted models: 6y5d

Deposition Authors: Pathare GR , Cavadini S
Structural mechanism of cGAS inhibition by the nucleosome.
Pathare GR , Decout A , Gluck S , Cavadini S, Makasheva K , Hovius R , Kempf G, Weiss J , Kozicka Z , Guey B , Melenec P , Fierz B , Thoma NH , Ablasser A
(2020) Nature , 587 , 668 - 672
PUBMED: 32911482
DOI: doi:10.1038/s41586-020-2750-6
ISSN: 1476-4687
ASTM: NATUAS