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EMD-10657

Single-particle
2.54 Å
EMD-10657
3D View Gallery
Deposition: 03/02/2020
Map released: 04/11/2020
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-10657
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6xzb summary report (pdf.gz) Map and 6xzb FULL report (pdf.gz)
EMICSS annotations (xml)

E. coli 70S ribosome in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet) (focused classification).

EMD-10657

Single-particle
2.54 Å
EMD-10657
3D View Gallery
Deposition: 03/02/2020
Map released: 04/11/2020
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli K-12, Saccharomyces cerevisiae
Sample: E. coli 70S ribosome in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).
Fitted models: 6xzb

Deposition Authors: Pichkur EB, Polikanov YS
Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome.
Pichkur EB, Paleskava A, Tereshchenkov AG , Kasatsky P, Komarova ES, Shiriaev DI, Bogdanov AA, Dontsova OA, Osterman IA, Sergiev PV, Polikanov YS , Myasnikov AG, Konevega AL
(2020) RNA , 26 , 715 - 723
PUBMED: 32144191
DOI: doi:10.1261/rna.073817.119
ISSN: 1469-9001
ASTM: RNARFU