EMD-10655

Single-particle
2.1 Å
EMD-10655
3D View Gallery
Deposition: 03/02/2020
Map released: 22/07/2020
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-10655

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6xz7 summary report (pdf.gz) Map-6xz7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).

EMD-10655

Single-particle
2.1 Å
EMD-10655
3D View Gallery
Deposition: 03/02/2020
Map released: 22/07/2020
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli (strain K12), Saccharomyces cerevisiae
Sample: E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).
Fitted models: 6xz7

Deposition Authors: Pichkur EB, Polikanov YS
Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to theE. coli70S ribosome.
Pichkur EB, Paleskava A, Tereshchenkov AG , Kasatsky P, Komarova ES, Shiriaev DI, Bogdanov AA, Dontsova OA, Osterman IA, Sergiev PV, Polikanov YS , Myasnikov AG, Konevega AL
(2020) RNA , 26 , 715 - 723
PUBMED: 32144191
DOI: doi:10.1261/rna.073817.119
ISSN: 1469-9001
ASTM: RNARFU