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EMD-10652
Multiple system atrophy Type II-2 alpha-synuclein filament
EMD-10652
Helical reconstruction3.09 Å
Deposition: 30/01/2020Map released: 12/02/2020
Last modified: 02/07/2025
Sample Organism:
Homo sapiens
Sample: Sarkosyl-insoluble fractions from the putamen of multiple system atrophy brain
Fitted models: 6xyq
Deposition Authors: Schweighauser M
,
Shi Y
Sample: Sarkosyl-insoluble fractions from the putamen of multiple system atrophy brain
Fitted models: 6xyq
Deposition Authors: Schweighauser M
,
Shi Y
Structures of alpha-synuclein filaments from multiple system atrophy.
Schweighauser M
,
Shi Y
,
Tarutani A
,
Kametani F
,
Murzin AG,
Ghetti B
,
Matsubara T
,
Tomita T
,
Ando T
,
Hasegawa K,
Murayama S,
Yoshida M,
Hasegawa M,
Scheres SHW
,
Goedert M
(2020) Nature , 585 , 464 - 469
,
Shi Y
,
Tarutani A
,
Kametani F
,
Murzin AG,
Ghetti B
,
Matsubara T
,
Tomita T
,
Ando T
,
Hasegawa K,
Murayama S,
Yoshida M,
Hasegawa M,
Scheres SHW
,
Goedert M
(2020) Nature , 585 , 464 - 469
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UP_A025_1013 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_U105184291 (United Kingdom)
- Innovative Medicines Initiative: 116060 (United Kingdom)
- Japan Agency for Medical Research and Development (AMED): JP18ek0109391 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP18dm020719 (Japan)
- National Institutes of Health/National Institute on Aging (NIH/NIA): P30AG010133 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): U01NS110437 (United States)
