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EMD-10514
Cryo-EM reconstruction of TypeII tau filaments extracted from the brains of individuals with Corticobasal degeneration
EMD-10514
Helical reconstruction3.0 Å
Deposition: 27/11/2019Map released: 05/02/2020
Last modified: 22/05/2024
Sample Organism:
Homo sapiens
Sample: Tau filaments extracted from the Frontal cortex of a patient with corticobasal degeneration.
Fitted models: 6tjx
Deposition Authors: Zhang W
,
Murzin AG,
Falcon B,
Shi Y,
Goedert M,
Scheres SHW
Sample: Tau filaments extracted from the Frontal cortex of a patient with corticobasal degeneration.
Fitted models: 6tjx
Deposition Authors: Zhang W
,
Murzin AG,
Falcon B,
Shi Y,
Goedert M,
Scheres SHW
Novel tau filament fold in corticobasal degeneration.
Zhang W
,
Tarutani A
,
Newell KL,
Murzin AG,
Matsubara T
,
Falcon B,
Vidal R
,
Garringer HJ
,
Shi Y,
Ikeuchi T
,
Murayama S,
Ghetti B
,
Hasegawa M,
Goedert M,
Scheres SHW
(2020) Nature , 580 , 283 - 287
,
Tarutani A
,
Newell KL,
Murzin AG,
Matsubara T
,
Falcon B,
Vidal R
,
Garringer HJ
,
Shi Y,
Ikeuchi T
,
Murayama S,
Ghetti B
,
Hasegawa M,
Goedert M,
Scheres SHW
(2020) Nature , 580 , 283 - 287
Grant Support:
- Medical Research Council (United Kingdom): MC_UP_A025_1013 (United Kingdom)
- Medical Research Council (United Kingdom): MC_U105184291 (United Kingdom)
