EMD-10512
Cryo-EM reconstruction of TypeI tau filaments extracted from the brains of an individual (Case 1) with Corticobasal degeneration
EMD-10512
Helical reconstruction3.2 Å
Deposition: 26/11/2019Map released: 05/02/2020
Last modified: 22/05/2024
Sample Organism:
Homo sapiens
Sample: Tau filaments extracted from the Frontal cortex of a patient with corticobasal degeneration.
Fitted models: 6tjo
Deposition Authors: Zhang W
,
Murzin AG,
Falcon B,
Shi Y,
Goedert M,
Scheres SHW
Sample: Tau filaments extracted from the Frontal cortex of a patient with corticobasal degeneration.
Fitted models: 6tjo
Deposition Authors: Zhang W
,
Murzin AG,
Falcon B,
Shi Y,
Goedert M,
Scheres SHW
Novel tau filament fold in corticobasal degeneration.
Zhang W ,
Tarutani A ,
Newell KL,
Murzin AG,
Matsubara T ,
Falcon B,
Vidal R ,
Garringer HJ ,
Shi Y,
Ikeuchi T ,
Murayama S,
Ghetti B ,
Hasegawa M,
Goedert M,
Scheres SHW
(2020) Nature , 580 , 283 - 287
,
Tarutani A ,
Newell KL,
Murzin AG,
Matsubara T ,
Falcon B,
Vidal R ,
Garringer HJ ,
Shi Y,
Ikeuchi T ,
Murayama S,
Ghetti B ,
Hasegawa M,
Goedert M,
Scheres SHW
(2020) Nature , 580 , 283 - 287
Grant Support:
- Medical Research Council (United Kingdom): MC_UP_A025_1013 (United Kingdom)
- Medical Research Council (United Kingdom): MC_U105184291 (United Kingdom)