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EMD-10277
Cryo-EM structure of human SERINC5 in LMNG micelles, bound to Fab.
EMD-10277
Single-particle8.2 Å
Deposition: 30/08/2019Map released: 01/01/2020
Last modified: 25/11/2020
Sample Organism:
Homo sapiens,
Mus musculus
Sample: complex of SERINC5 with FAB bound to ECL4 in LMNG micelles
Deposition Authors: Rosa A, Pye VE, Nans A, Cherepanov P
Sample: complex of SERINC5 with FAB bound to ECL4 in LMNG micelles
Deposition Authors: Rosa A, Pye VE, Nans A, Cherepanov P
A bipartite structural organization defines the SERINC family of HIV-1 restriction factors.
Pye VE 
,
Rosa A,
Bertelli C ,
Struwe WB ,
Maslen SL,
Corey R,
Liko I,
Hassall M,
Mattiuzzo G ,
Ballandras-Colas A ,
Nans A ,
Takeuchi Y,
Stansfeld PJ ,
Skehel JM,
Robinson CV,
Pizzato M ,
Cherepanov P
(2020) Nat. Struct. Mol. Biol. , 27 , 78 - 83
,
Rosa A,
Bertelli C ,
Struwe WB ,
Maslen SL,
Corey R,
Liko I,
Hassall M,
Mattiuzzo G ,
Ballandras-Colas A ,
Nans A ,
Takeuchi Y,
Stansfeld PJ ,
Skehel JM,
Robinson CV,
Pizzato M ,
Cherepanov P
(2020) Nat. Struct. Mol. Biol. , 27 , 78 - 83
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases: P50 AI150481 (United States)
- The Francis Crick Institute: FC001061 (United Kingdom)