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EMD-10213
Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and Indisulam
EMD-10213
Single-particle3.54 Å
Deposition: 12/08/2019Map released: 18/12/2019
Last modified: 23/10/2024
Sample Organism:
Homo sapiens
Sample: DDB1 complex
Fitted models: 6sj7
Deposition Authors: Srinivas H
Sample: DDB1 complex
Fitted models: 6sj7
Deposition Authors: Srinivas H
Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Bussiere DE 
,
Xie L ,
Srinivas H,
Shu W,
Burke A,
Be C,
Zhao J,
Godbole A,
King D,
Karki RG ,
Hornak V ,
Xu F,
Cobb J,
Carte N,
Frank AO ,
Frommlet A ,
Graff P,
Knapp M,
Fazal A ,
Okram B,
Jiang S,
Michellys PY,
Beckwith R ,
Voshol H,
Wiesmann C,
Solomon JM ,
Paulk J
(2020) Nat Chem Biol , 16 , 15 - 23
,
Xie L ,
Srinivas H,
Shu W,
Burke A,
Be C,
Zhao J,
Godbole A,
King D,
Karki RG ,
Hornak V ,
Xu F,
Cobb J,
Carte N,
Frank AO ,
Frommlet A ,
Graff P,
Knapp M,
Fazal A ,
Okram B,
Jiang S,
Michellys PY,
Beckwith R ,
Voshol H,
Wiesmann C,
Solomon JM ,
Paulk J
(2020) Nat Chem Biol , 16 , 15 - 23