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EMD-0917
Cryo-EM structure of the human glucagon receptor in complex with Gs
EMD-0917
Single-particle3.7 Å
Deposition: 26/12/2019Map released: 01/04/2020
Last modified: 30/10/2024
Sample Organism:
Homo sapiens,
Lama glama
Sample: Complex of glucagon receptor bound to glucagon, Gs protein and nanobody
Fitted models: 6lmk
Deposition Authors: Qiao A
,
Han S
Sample: Complex of glucagon receptor bound to glucagon, Gs protein and nanobody
Fitted models: 6lmk
Deposition Authors: Qiao A
,
Han S
Structural basis of Gsand Girecognition by the human glucagon receptor.
Qiao A ,
Han S ,
Li X ,
Li Z ,
Zhao P ,
Dai A ,
Chang R ,
Tai L ,
Tan Q ,
Chu X ,
Ma L ,
Thorsen TS ,
Reedtz-Runge S ,
Yang D ,
Wang MW ,
Sexton PM ,
Wootten D ,
Sun F ,
Zhao Q ,
Wu B
(2020) Science , 367 , 1346 - 1352
,
Han S ,
Li X ,
Li Z ,
Zhao P ,
Dai A ,
Chang R ,
Tai L ,
Tan Q ,
Chu X ,
Ma L ,
Thorsen TS ,
Reedtz-Runge S ,
Yang D ,
Wang MW ,
Sexton PM ,
Wootten D ,
Sun F ,
Zhao Q ,
Wu B
(2020) Science , 367 , 1346 - 1352
Grant Support:
- Ministry of Science and Technology (MoST, China): 2018YFA0507000 (China)
- Ministry of Science and Technology (MoST, China): 2017YFA0504703 (China)
- National Science Foundation (NSF, China): 31825010 (China)
- National Science Foundation (NSF, China): 81525024 (China)
- National Science Foundation (NSF, China): 31830020 (China)
- Chinese Academy of Sciences: QYZDB-SSW-SMC024 (China)
- Chinese Academy of Sciences: QYZDB-SSW-SMC054 (China)
- Ministry of Science and Technology (MoST, China): 2018ZX09711002 (China)