EMD-0568

Single-particle
4.11 Å
EMD-0568
3D View Gallery
Deposition: 16/02/2019
Map released: 01/05/2019
Last modified: 08/05/2019
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-0568

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM 3D map of human ATP-citrate lyase N-terminal segment in complex with inhibitor NDI-091143

EMD-0568

Single-particle
4.11 Å
EMD-0568
3D View Gallery
Deposition: 16/02/2019
Map released: 01/05/2019
Last modified: 08/05/2019
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: protein-inhibitor complex

Deposition Authors: Wei J, Tong L
An allosteric mechanism for potent inhibition of human ATP-citrate lyase.
Wei J, Leit S, Kuai J, Therrien E , Rafi S, Harwood Jr HJ, DeLaBarre B, Tong L
(2019) Nature , 568 , 566 - 570
PUBMED: 30944472
DOI: doi:10.1038/s41586-019-1094-6
ISSN: 1476-4687
ASTM: NATUAS