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EMD-0567

Single-particle
3.67 Å
EMD-0567
3D View Gallery
Deposition: 16/02/2019
Map released: 17/04/2019
Last modified: 20/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-0567
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6o0h summary report (pdf.gz) Map and 6o0h FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143

EMD-0567

Single-particle
3.67 Å
EMD-0567
3D View Gallery
Deposition: 16/02/2019
Map released: 17/04/2019
Last modified: 20/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: protein-inhibitor complex
Fitted models: 6o0h

Deposition Authors: Wei J, Tong L
An allosteric mechanism for potent inhibition of human ATP-citrate lyase.
Wei J, Leit S, Kuai J, Therrien E , Rafi S, Harwood Jr HJ, DeLaBarre B, Tong L
(2019) Nature , 568 , 566 - 570
PUBMED: 30944472
DOI: doi:10.1038/s41586-019-1094-6
ISSN: 1476-4687
ASTM: NATUAS