EMD-0476

Single-particle
3.8 Å
EMD-0476
3D View Gallery
Deposition: 18/01/2019
Map released: 19/06/2019
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-0476

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6npy summary report (pdf.gz) Map-6npy FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of NLRP3 bound to NEK7

EMD-0476

Single-particle
3.8 Å
EMD-0476
3D View Gallery
Deposition: 18/01/2019
Map released: 19/06/2019
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NL3-NEK7
Fitted models: 6npy

Deposition Authors: Sharif H , Wang L, Wu H
Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome.
Sharif H , Wang L, Wang WL, Magupalli VG, Andreeva L , Qiao Q, Hauenstein AV , Wu Z, Nunez G, Mao Y , Wu H
(2019) Nature , 570 , 338 - 343
PUBMED: 31189953
DOI: doi:10.1038/s41586-019-1295-z
ISSN: 1476-4687
ASTM: NATUAS