EMDB < EMD-0350

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

EMD-0350

Single-particle
6.3 Å

EMD-0350

3D View Gallery

Deposition: 23/11/2018
Map released: 20/03/2019
Last modified: 20/03/2019

Overview 3D View Sample Experiment Validation Additional data Links

Overview 3D View Sample Experiment Validation Additional data Links

EMD-0350

Download

Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus

EMD-0350

Single-particle
6.3 Å
EMD-0350

EMD-0350

3D View Gallery

Deposition: 23/11/2018
Map released: 20/03/2019
Last modified: 20/03/2019

Overview 3D View Sample Experiment Validation Additional data Links

Name: DS-Cav1-I53-50 nanoparticle

Summary:

Complex

DS-Cav1-I53-50 nanoparticle

Protein

Engineered respiratory syncytial virus F protein (DS-Cav-1) fused to the foldon and to the trimeric component of I53-50 (DS-Cav1-I53-50A)
Pentameric component of I53-50 (I53-50B)

Complex [1]

Name: DS-Cav1-I53-50 nanoparticle

Natural source [1]

Organism: Respiratory syncytial virus

Recombinant Expression [1]

Organism	Strain	Cell	Plasmid
Homo sapiens	-	-	-

Protein [2]

LEVO

Name: Engineered respiratory syncytial virus F protein (DS-Cav-1) fused to the foldon and to the trimeric component of I53-50 (DS-Cav1-I53-50A)

Natural source

Organism: Respiratory syncytial virus

LEVO

Name: Pentameric component of I53-50 (I53-50B)

Natural source

Organism: Respiratory syncytial virus