EMD-0062

Single-particle
4.24 Å
EMD-0062
3D View Gallery
Deposition: 18/06/2018
Map released: 19/12/2018
Last modified: 15/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-0062

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6gtd summary report (pdf.gz) Map-6gtd FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Transient state structure of CRISPR-Cpf1 (Cas12a). I2 conformation

EMD-0062

Single-particle
4.24 Å
EMD-0062
3D View Gallery
Deposition: 18/06/2018
Map released: 19/12/2018
Last modified: 15/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Francisella tularensis subsp. novicida U112
Sample: TRansition state complex I2 conformation
Fitted models: 6gtd

Deposition Authors: Montoya G , Mesa P
Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Stella S , Mesa P, Thomsen J , Paul B , Alcon P , Jensen SB , Saligram B, Moses ME , Hatzakis NS , Montoya G
(2018) Cell , 175 , 1856 - 1871.e21
PUBMED: 30503205
DOI: doi:10.1016/j.cell.2018.10.045
ISSN: 1097-4172
Grant Support: