EMD-18570

Helical reconstruction
2.5 Å
EMD-18570
3D View Gallery
Deposition: 03/10/2023
Map released: 04/09/2024
Last modified: 04/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18570

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8qpz summary report (pdf.gz) Map-8qpz FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of recombinant DeltaN7 alpha-synuclein in PBS

EMD-18570

Helical reconstruction
2.5 Å
EMD-18570
3D View Gallery
Deposition: 03/10/2023
Map released: 04/09/2024
Last modified: 04/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: alpha-synuclein DeltaN7 amyloid fibrils
Fitted models: 8qpz

Deposition Authors: Thacker D, Wilkinson M , Dewison KM , Ranson NA , Brockwell DJ , Radford SE
Residues 2 to 7 of alpha-synuclein regulate amyloid formation via lipid-dependent and lipid-independent pathways.
Dewison KM , Rowlinson B , Machin JM , Crossley JA , Thacker D, Wilkinson M , Ulamec SM, Khan GN , Ranson NA , van Oosten-Hawle P , Brockwell DJ , Radford SE
(2024) PNAS , 121 , e2315006121 - e2315006121
PUBMED: 39133842
DOI: doi:10.1073/pnas.2315006121
ISSN: 1091-6490
ASTM: PNASA6