CHEBI:6950 - mirtazapine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name mirtazapine
ChEBI ID CHEBI:6950
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C17H19N3
Net Charge 0
Average Mass 265.35290
Monoisotopic Mass 265.15790
InChI InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
InChIKey RONZAEMNMFQXRA-UHFFFAOYSA-N
SMILES CN1CCN2C(C1)c1ccccc1Cc1cccnc21
Roles Classification
Biological Role(s): alpha-adrenergic antagonist
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
Application(s): alpha-adrenergic antagonist
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
anxiolytic drug
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
oneirogen
Any substance that produces or enhances dream-like states of consciousness.
antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
(via tetracyclic antidepressant )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing mirtazapine (CHEBI:6950) has role α-adrenergic antagonist (CHEBI:37890)
mirtazapine (CHEBI:6950) has role anxiolytic drug (CHEBI:35474)
mirtazapine (CHEBI:6950) has role H1-receptor antagonist (CHEBI:37955)
mirtazapine (CHEBI:6950) has role histamine antagonist (CHEBI:37956)
mirtazapine (CHEBI:6950) has role oneirogen (CHEBI:146270)
mirtazapine (CHEBI:6950) has role serotonergic antagonist (CHEBI:48279)
mirtazapine (CHEBI:6950) is a benzazepine (CHEBI:35676)
mirtazapine (CHEBI:6950) is a tetracyclic antidepressant (CHEBI:50940)
IUPAC Name
2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
INNs Sources
mirtazapina ChEBI
mirtazapine ChEBI
mirtazapinum ChEBI
Synonyms Sources
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine ChemIDplus
Mirtazapine KEGG COMPOUND
Manual Xrefs Databases
1816 DrugCentral
2980 VSDB
C07570 KEGG COMPOUND
D00563 KEGG DRUG
DB00370 DrugBank
DE2614406 Patent
LSM-1706 LINCS
Mirtazapine Wikipedia
US4062848 Patent
View more database links
Registry Numbers Types Sources
549345 Beilstein Registry Number Beilstein
61337-67-5 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
10446735 PubMed citation Europe PMC
10653218 PubMed citation Europe PMC
16965209 PubMed citation Europe PMC
18548827 PubMed citation Europe PMC
33163376 PubMed citation Europe PMC
33422759 PubMed citation Europe PMC
33559900 PubMed citation Europe PMC
33685359 PubMed citation Europe PMC
33841403 PubMed citation Europe PMC
33856954 PubMed citation Europe PMC
Last Modified
08 July 2021