CHEBI:6950 - mirtazapine

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ChEBI Name mirtazapine
ChEBI ID CHEBI:6950
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C17H19N3
Net Charge 0
Average Mass 265.35290
Monoisotopic Mass 265.158
InChI InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
InChIKey RONZAEMNMFQXRA-UHFFFAOYSA-N
SMILES CN1CCN2C(C1)c1ccccc1Cc1cccnc21
Roles Classification
Biological Role(s): alpha-adrenergic antagonist
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
Application(s): alpha-adrenergic antagonist
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
anxiolytic drug
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
(via tetracyclic antidepressant )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing mirtazapine (CHEBI:6950) has role α-adrenergic antagonist (CHEBI:37890)
mirtazapine (CHEBI:6950) has role anxiolytic drug (CHEBI:35474)
mirtazapine (CHEBI:6950) has role H1-receptor antagonist (CHEBI:37955)
mirtazapine (CHEBI:6950) has role histamine antagonist (CHEBI:37956)
mirtazapine (CHEBI:6950) has role serotonergic antagonist (CHEBI:48279)
mirtazapine (CHEBI:6950) is a benzazepine (CHEBI:35676)
mirtazapine (CHEBI:6950) is a tetracyclic antidepressant (CHEBI:50940)
IUPAC Name
2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
INNs Sources
mirtazapina ChEBI
mirtazapine ChEBI
mirtazapinum ChEBI
Synonyms Sources
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine ChemIDplus
Mirtazapine KEGG COMPOUND
Manual Xrefs Databases
1816 DrugCentral
2980 VSDB
C07570 KEGG COMPOUND
D00563 KEGG DRUG
DB00370 DrugBank
DE2614406 Patent
LSM-1706 LINCS
Mirtazapine Wikipedia
US4062848 Patent
View more database links
Registry Numbers Types Sources
549345 Beilstein Registry Number Beilstein
61337-67-5 CAS Registry Number ChemIDplus
Last Modified
22 February 2017