CHEBI:51032 - epinastine

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ChEBI Name epinastine
ChEBI ID CHEBI:51032
Definition A benzazepine that is 6,11-dihydro-5H-dibenzo[b,e]azepine in which the azepine ring is fused to the e side of 4,5-dihydro-1H-imidazol-2-amine.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C16H15N3
Net Charge 0
Average Mass 249.31040
Monoisotopic Mass 249.127
InChI InChI=1S/C16H15N3/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16/h1-8,15H,9-10H2,(H2,17,18)
InChIKey WHWZLSFABNNENI-UHFFFAOYSA-N
SMILES NC1=NCC2N1c1ccccc1Cc1ccccc21
Roles Classification
Biological Role(s): histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
Application(s): anti-allergic agent
A drug used to treat allergic reactions.
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
ophthalmology drug
Any compound used for the treatment of eye conditions or eye diseases.
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing epinastine (CHEBI:51032) has role anti-allergic agent (CHEBI:50857)
epinastine (CHEBI:51032) has role H1-receptor antagonist (CHEBI:37955)
epinastine (CHEBI:51032) has role histamine antagonist (CHEBI:37956)
epinastine (CHEBI:51032) has role ophthalmology drug (CHEBI:66981)
epinastine (CHEBI:51032) is a benzazepine (CHEBI:35676)
epinastine (CHEBI:51032) is a guanidines (CHEBI:24436)
Incoming epinastine hydrochloride (CHEBI:51037) has part epinastine (CHEBI:51032)
R-epinastine (CHEBI:51035) is a epinastine (CHEBI:51032)
S-epinastine (CHEBI:51036) is a epinastine (CHEBI:51032)
IUPAC Name
9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine
INNs Sources
epinastina ChemIDplus
épinastine ChemIDplus
epinastine ChemIDplus
epinastinum ChemIDplus
Synonyms Sources
(±)-epinastine ChemIDplus
3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepine ChemIDplus
Manual Xrefs Databases
1027 DrugCentral
D07900 KEGG DRUG
DB00751 DrugBank
Epinastine Wikipedia
GB2071095 Patent
US4313931 Patent
View more database links
Registry Numbers Types Sources
3593307 Reaxys Registry Number Reaxys
3593307 Beilstein Registry Number Beilstein
80012-43-7 CAS Registry Number ChemIDplus
Last Modified
22 February 2017