CHEBI:50091 - S-nitrosoglutathione

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ChEBI Name S-nitrosoglutathione
ChEBI ID CHEBI:50091
ChEBI ASCII Name S-nitrosoglutathione
Definition A glutathione derivative that is glutathione in which the hydrogen attached to the sulfur has been replaced by sulfur has been replaced by a nitroso group.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C10H16N4O7S
Net Charge 0
Average Mass 336.320
Monoisotopic Mass 336.07397
InChI InChI=1S/C10H16N4O7S/c11-5(10(19)20)1-2-7(15)13-6(4-22-14-21)9(18)12-3-8(16)17/h5-6H,1-4,11H2,(H,12,18)(H,13,15)(H,16,17)(H,19,20)/t5-,6-/m0/s1
InChIKey HYHSBSXUHZOYLX-WDSKDSINSA-N
SMILES N[C@@H](CCC(=O)N[C@@H](CSN=O)C(=O)NCC(=O)O)C(=O)O
Roles Classification
Chemical Role(s): nitric oxide donor
An agent, with unique chemical structure and biochemical requirements, which generates nitric oxide.
Biological Role(s): signalling molecule
A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell.
Application(s): platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
bronchodilator agent
An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
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ChEBI Ontology
Outgoing S-nitrosoglutathione (CHEBI:50091) has role bronchodilator agent (CHEBI:35523)
S-nitrosoglutathione (CHEBI:50091) has role nitric oxide donor (CHEBI:50566)
S-nitrosoglutathione (CHEBI:50091) has role platelet aggregation inhibitor (CHEBI:50427)
S-nitrosoglutathione (CHEBI:50091) has role signalling molecule (CHEBI:62488)
S-nitrosoglutathione (CHEBI:50091) is a glutathione derivative (CHEBI:24337)
S-nitrosoglutathione (CHEBI:50091) is a nitrosothio compound (CHEBI:145545)
S-nitrosoglutathione (CHEBI:50091) is conjugate acid of S-nitrosoglutathione(1−) (CHEBI:145544)
S-nitrosoglutathione (CHEBI:50091) is conjugate acid of L-γ-glutamyl-S-nitroso-D-cysteinylglycine(2−) (CHEBI:43056)
Incoming S-nitrosoglutathione(1−) (CHEBI:145544) is conjugate base of S-nitrosoglutathione (CHEBI:50091)
L-γ-glutamyl-S-nitroso-D-cysteinylglycine(2−) (CHEBI:43056) is conjugate base of S-nitrosoglutathione (CHEBI:50091)
IUPAC Name
L-γ-glutamyl-S-nitroso-L-cysteinylglycine
Synonyms Sources
glutathione thionitrite ChemIDplus
GSNO ChemIDplus
N-(N-L-γ-glutamyl-S-nitroso-L-cysteinyl)glycine ChemIDplus
nitrosoglutathione ChemIDplus
SNOG ChemIDplus
Registry Numbers Types Sources
3566211 Beilstein Registry Number ChemIDplus
57564-91-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
10070107 PubMed citation Europe PMC
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Last Modified
17 January 2020