CHEBI:3127 - bisoprolol

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ChEBI Name bisoprolol
ChEBI ID CHEBI:3127
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C18H31NO4
Net Charge 0
Average Mass 325.44308
Monoisotopic Mass 325.225
InChI InChI=1S/C18H31NO4/c1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4/h5-8,14-15,17,19-20H,9-13H2,1-4H3
InChIKey VHYCDWMUTMEGQY-UHFFFAOYSA-N
SMILES CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
sympatholytic agent
Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS).
Application(s): antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
anti-arrhythmia drug
A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
sympatholytic agent
Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing bisoprolol (CHEBI:3127) has role β-adrenergic antagonist (CHEBI:35530)
bisoprolol (CHEBI:3127) has role anti-arrhythmia drug (CHEBI:38070)
bisoprolol (CHEBI:3127) has role antihypertensive agent (CHEBI:35674)
bisoprolol (CHEBI:3127) has role sympatholytic agent (CHEBI:66991)
bisoprolol (CHEBI:3127) is a secondary alcohol (CHEBI:35681)
bisoprolol (CHEBI:3127) is a secondary amine (CHEBI:32863)
Incoming bisoprolol fumarate (CHEBI:3128) has part bisoprolol (CHEBI:3127)
IUPAC Name
1-{4-[(2-isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol
INNs Sources
bisoprolol WHO MedNet
bisoprolol ChemIDplus
bisoprololum WHO MedNet
Synonyms Sources
(+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol ChemIDplus
(RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol ChemIDplus
Bisoprolol KEGG COMPOUND
Manual Xrefs Databases
380 DrugCentral
BE859425 Patent
Bisoprolol Wikipedia
C06852 KEGG COMPOUND
D02342 KEGG DRUG
DB00612 DrugBank
LSM-1886 LINCS
US4258062 Patent
View more database links
Registry Number Type Source
66722-44-9 CAS Registry Number ChemIDplus
Last Modified
22 February 2017