CHEBI:23965 - estradiol

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name estradiol
Definition A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:42364
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C18H24O2
Net Charge 0
Average Mass 272.38196
Monoisotopic Mass 272.17763
InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17?,18+/m1/s1
SMILES [H][C@]12CC[C@]3(C)C(O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21
Roles Classification
Biological Role(s): human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing estradiol (CHEBI:23965) has parent hydride estrane (CHEBI:23966)
estradiol (CHEBI:23965) has role estrogen (CHEBI:50114)
estradiol (CHEBI:23965) has role human metabolite (CHEBI:77746)
estradiol (CHEBI:23965) is a 17-hydroxy steroid (CHEBI:36838)
estradiol (CHEBI:23965) is a 3-hydroxy steroid (CHEBI:36834)
estradiol (CHEBI:23965) is a phenolic steroid (CHEBI:177917)
Incoming 17α-ethynylestradiol (CHEBI:4903) has functional parent estradiol (CHEBI:23965)
ulipristal acetate (CHEBI:71025) has functional parent estradiol (CHEBI:23965)
17α-estradiol (CHEBI:17160) is a estradiol (CHEBI:23965)
17β-estradiol (CHEBI:16469) is a estradiol (CHEBI:23965)
Synonym Source
oestradiol ChEBI
Manual Xref Database
Estradiol Wikipedia
View more database links
Citations Waiting for Citations Types Sources
10696569 PubMed citation Europe PMC
24084694 PubMed citation Europe PMC
Last Modified
23 September 2021