CHEBI:12071 - 5,10-methylenetetrahydrofolate(2−)

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ChEBI Name 5,10-methylenetetrahydrofolate(2−)
ChEBI ASCII Name 5,10-methylenetetrahydrofolate(2-)
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C20H21N7O6
Net Charge -2
Average Mass 455.42432
Monoisotopic Mass 455.15643
InChI InChI=1S/C20H23N7O6/c21-20-24-16-15(18(31)25-20)27-9-26(8-12(27)7-22-16)11-3-1-10(2-4-11)17(30)23-13(19(32)33)5-6-14(28)29/h1-4,12-13H,5-9H2,(H,23,30)(H,28,29)(H,32,33)(H4,21,22,24,25,31)/p-2/t12?,13-/m0/s1
SMILES Nc1nc2NCC3CN(CN3c2c(=O)[nH]1)c1ccc(cc1)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O
Metabolite of Species Details
Saccharomyces cerevisiae (NCBI:txid4932) Source: See: PubMed
Roles Classification
Biological Role(s): Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
water-soluble vitamin (role)
Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.
(via B vitamin )
Application(s): nutraceutical
A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
(via B vitamin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 5,10-methylenetetrahydrofolate(2−) (CHEBI:12071) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
5,10-methylenetetrahydrofolate(2−) (CHEBI:12071) is a dicarboxylic acid dianion (CHEBI:28965)
5,10-methylenetetrahydrofolate(2−) (CHEBI:12071) is a tetrahydrofolate (CHEBI:67016)
5,10-methylenetetrahydrofolate(2−) (CHEBI:12071) is conjugate base of 5,10-methylenetetrahydrofolic acid (CHEBI:20502)
Incoming (6R)-5,10-methylenetetrahydrofolate(2−) (CHEBI:15636) is a 5,10-methylenetetrahydrofolate(2−) (CHEBI:12071)
5,10-methylenetetrahydrofolic acid (CHEBI:20502) is conjugate acid of 5,10-methylenetetrahydrofolate(2−) (CHEBI:12071)
Synonym Source
5,10-methylenetetrahydrofolate UniProt
Last Modified
21 January 2016