CHEBI:73167 - concanamycin A

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ChEBI Name concanamycin A
ChEBI ID CHEBI:73167
Definition A concanamycin in which the lactone ring contains 4 double bonds and is substituted by 4 methyl groups, 2 hydroxy groups, 2 methoxy groups and an ethyl group.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Johnny Lloyd
Supplier Information
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Formula C46H75NO14
Net Charge 0
Average Mass 866.08600
Monoisotopic Mass 865.51876
InChI InChI=1S/C46H75NO14/c1-13-16-34-28(7)37(58-38-22-33(48)43(31(10)57-38)60-45(47)53)23-46(54,61-34)30(9)41(51)29(8)42-35(55-11)18-15-17-24(3)19-26(5)39(49)32(14-2)40(50)27(6)20-25(4)21-36(56-12)44(52)59-42/h13,15-18,20-21,26-35,37-43,48-51,54H,14,19,22-23H2,1-12H3,(H2,47,53)/b16-13+,18-15+,24-17+,25-20+,36-21-/t26-,27-,28-,29+,30+,31-,32+,33-,34-,35+,37-,38+,39+,40-,41-,42-,43-,46-/m1/s1
InChIKey DJZCTUVALDDONK-HQMSUKCRSA-N
SMILES [H][C@@]1(OC(=O)\C(OC)=C\C(C)=C\[C@@H](C)[C@@H](O)[C@@H](CC)[C@@H](O)[C@H](C)C\C(C)=C\C=C\[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](O[C@H]2C[C@@H](O)[C@H](OC(N)=O)[C@@H](C)O2)[C@H](C)[C@H](O1)\C=C\C
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of H+-transporting two-sector ATPase inhibitor (EC 3.6.3.14).
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
(via concanamycin )
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via macrolide antibiotic )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing concanamycin A (CHEBI:73167) has role antifungal agent (CHEBI:35718)
concanamycin A (CHEBI:73167) has role EC 3.6.3.14 (H+-transporting two-sector ATPase) inhibitor (CHEBI:73214)
concanamycin A (CHEBI:73167) has role metabolite (CHEBI:25212)
concanamycin A (CHEBI:73167) is a carbamate ester (CHEBI:23003)
concanamycin A (CHEBI:73167) is a concanamycin (CHEBI:73195)
IUPAC Name
(5R)-3-O-(4-O-carbamoyl-2,6-dideoxy-β-D-arabino-hexopyranosyl)-2,4-dideoxy-1-C-{(2S,3R,4S)-4-[(2R,3S,4E,6E,9R,10S,11S,12R,13R,14E,16Z)-11-ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxypentan-2-yl}-4-methyl-5-[(1E)-prop-1-en-1-yl]-α-D-threo-pentopyranose
Synonym Source
folimycin ChEBI
Manual Xref Database
C15761 KEGG COMPOUND
View more database links
Registry Number Type Source
80890-47-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
11297425 PubMed citation Europe PMC
12186879 PubMed citation Europe PMC
15638326 PubMed citation Europe PMC
18387916 PubMed citation Europe PMC
23038011 PubMed citation Europe PMC
6511660 PubMed citation Europe PMC
8024571 PubMed citation Europe PMC
8050591 PubMed citation Europe PMC
8242793 PubMed citation Europe PMC
8391816 PubMed citation Europe PMC
8621902 PubMed citation Europe PMC
Last Modified
04 August 2014