CHEBI:65596 - cassiarin A

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ChEBI Name cassiarin A
ChEBI ID CHEBI:65596
Definition An isoquinoline alkaloid that is pyrano[2,3,4-ij]isoquinoline substituted by a hydroxy group at position 8 and methyl groups at positions 2 and 5. It is isolated from the leaves of Cassia siamea and exhibits antiplasmodial activity against Plasmodium falciparum.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C13H11NO2
Net Charge 0
Average Mass 213.23190
Monoisotopic Mass 213.07898
InChI InChI=1S/C13H11NO2/c1-7-3-9-5-10(15)6-12-13(9)11(14-7)4-8(2)16-12/h3-6,15H,1-2H3
InChIKey PEFIRMBVFBVVGZ-UHFFFAOYSA-N
SMILES Cc1cc2cc(O)cc3oc(C)cc(n1)c23
Metabolite of Species Details
Senna siamea (NCBI:txidtxid346999) Found in leaf (BTO:0000713). See: PubMed
Roles Classification
Biological Role(s): antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing cassiarin A (CHEBI:65596) has role antimalarial (CHEBI:38068)
cassiarin A (CHEBI:65596) has role metabolite (CHEBI:25212)
cassiarin A (CHEBI:65596) is a cyclic ether (CHEBI:37407)
cassiarin A (CHEBI:65596) is a isoquinoline alkaloid (CHEBI:24921)
cassiarin A (CHEBI:65596) is a isoquinolines (CHEBI:24922)
cassiarin A (CHEBI:65596) is a organic heterotricyclic compound (CHEBI:26979)
cassiarin A (CHEBI:65596) is a phenols (CHEBI:33853)
IUPAC Name
2,5-dimethylpyrano[2,3,4-ij]isoquinolin-8-ol
Registry Number Type Source
11166745 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
17685627 PubMed citation Europe PMC
18412353 PubMed citation Europe PMC
18570405 PubMed citation Europe PMC
19892554 PubMed citation Europe PMC
20460764 PubMed citation Europe PMC
Last Modified
07 December 2012