buzepide metiodide (CHEBI:135429)

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ChEBI Name	buzepide metiodide

ChEBI ID	CHEBI:135429

Definition	An organic iodide salt of buzepide. It is a component of the antispasmodic drug vesadol.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C23H31N2O.I

Net Charge

Average Mass

478.418

Monoisotopic Mass

478.14811

InChI

InChI=1S/C23H30N2O.HI/c1-25(17-10-2-3-11-18-25)19-16-23(22(24)26,20-12-6-4-7-13-20)21-14-8-5-9-15-21;/h4-9,12-15H,2-3,10-11,16-19H2,1H3,(H-,24,26);1H

InChIKey

HMFBCJNMIYZRKQ-UHFFFAOYSA-N

SMILES

[I-].C[N+]1(CCC(C(N)=O)(C2=CC=CC=C2)C2=CC=CC=C2)CCCCCC1

Roles Classification
Biological Role(s):	cholinergic antagonist Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.

Application(s):	antispasmodic drug A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder. cholinergic antagonist Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.

ChEBI Ontology
Outgoing	buzepide metiodide (CHEBI:135429) has part buzepide(1+) (CHEBI:157622) buzepide metiodide (CHEBI:135429) has role antispasmodic drug (CHEBI:53784) buzepide metiodide (CHEBI:135429) has role cholinergic antagonist (CHEBI:48873) buzepide metiodide (CHEBI:135429) is a organic iodide salt (CHEBI:50356)

IUPAC Name

1-(4-amino-4-oxo-3,3-diphenylbutyl)-1-methylazepanium iodide

Synonyms	Sources
1-(3-carbamoyl-3,3-diphenylpropyl)-1-methylazepan-1-ium iodide	ChEBI
1-(3-carbamoyl-3,3-diphenylpropyl)hexahydro-1-methylazepinium iodide	ChEBI
1-(4-amino-4-oxo-3,3-diphenylbutyl)-1-methylazepan-1-ium iodide	IUPAC
buzepide methiodide	ChemIDplus
difexamide methiodide	DrugCentral
diphexamide iodomethylate	DrugCentral
diphexamide methiodide	ChemIDplus
F.I. 6146	ChemIDplus
FI 6146	ChemIDplus
metazepium iodide	DrugCentral
N-(3,3-diphenyl-3-carbamoylpropyl)-N-methylperhydroazepinium iodide	ChEBI
Spactin	ChemIDplus

Registry Number	Type	Source
15351-05-0	CAS Registry Number	ChemIDplus

Last Modified

09 October 2020