CHEBI:77939 - oroxylin A(1−)

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ChEBI Name oroxylin A(1−)
ChEBI ID CHEBI:77939
ChEBI ASCII Name oroxylin A(1-)
Definition A flavonoid oxoanion obtained by deprotonation of the 7-hydroxy group of oroxylin A. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.).
Stars This entity has been manually annotated by the ChEBI Team.
Submitter KAX
Supplier Information
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Formula C16H11O5
Net Charge -1
Average Mass 283.25610
Monoisotopic Mass 283.06120
InChI InChI=1S/C16H12O5/c1-20-16-11(18)8-13-14(15(16)19)10(17)7-12(21-13)9-5-3-2-4-6-9/h2-8,18-19H,1H3/p-1
InChIKey LKOJGSWUMISDOF-UHFFFAOYSA-M
SMILES COc1c([O-])cc2oc(cc(=O)c2c1O)-c1ccccc1
Roles Classification
Biological Role(s): EC 1.14.13.39 (nitric oxide synthase) inhibitor
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of nitric oxide synthase (EC 1.14.13.39).
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing oroxylin A(1−) (CHEBI:77939) has role antineoplastic agent (CHEBI:35610)
oroxylin A(1−) (CHEBI:77939) has role EC 1.14.13.39 (nitric oxide synthase) inhibitor (CHEBI:61908)
oroxylin A(1−) (CHEBI:77939) is a flavonoid oxoanion (CHEBI:60038)
oroxylin A(1−) (CHEBI:77939) is conjugate base of oroxylin A (CHEBI:61668)
Incoming oroxylin A (CHEBI:61668) is conjugate acid of oroxylin A(1−) (CHEBI:77939)
IUPAC Name
5-hydroxy-6-methoxy-4-oxo-2-phenyl-4H-chromen-7-olate
Synonym Source
oroxylin A UniProt
Last Modified
10 June 2014