CHEBI:91198 - LY 364947

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ChEBI Name LY 364947 ChEBI ID CHEBI:91198 Definition A member of the class of pyrazoles carrying pyridin-2-yl and quinolin-4-yl substituents at positions 3 and 4 respectively. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Formula C17H12N4 Net Charge 0 Average Mass 272.305 Monoisotopic Mass 272.10620 InChI InChI=1S/C17H12N4/c1-2-6-15-13(5-1)12(8-10-19-15)14-11-20-21-17(14)16-7-3-4-9-18-16/h1-11H,(H,20,21) InChIKey IBCXZJCWDGCXQT-UHFFFAOYSA-N SMILES N1=C2C(C=CC=C2)=C(C=C1)C3=CNN=C3C=4N=CC=CC4 Roles Classification Biological Role(s): TGFbeta receptor antagonist An antagonist that binds to and deactivates TGFbeta receptors. View more via ChEBI Ontology ChEBI Ontology Outgoing LY 364947 (CHEBI:91198) has role TGFβ receptor antagonist (CHEBI:91202) LY 364947 (CHEBI:91198) is a pyrazoles (CHEBI:26410) LY 364947 (CHEBI:91198) is a pyridines (CHEBI:26421) LY 364947 (CHEBI:91198) is a quinolines (CHEBI:26513) IUPAC Name 4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline Synonyms Sources HTS 466284 ChEBI LY-364947 ChEBI LY364947 ChEBI Registry Number Type Source 9492522 Reaxys Registry Number Reaxys Citations Types Sources 23721184 PubMed citation Europe PMC 24535220 PubMed citation Europe PMC 24742493 PubMed citation Europe PMC 25155999 PubMed citation Europe PMC 25566828 PubMed citation Europe PMC 26047759 PubMed citation Europe PMC 26751819 PubMed citation Europe PMC Last Modified 14 July 2016