CHEBI:194124 - akebia saponin D

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name akebia saponin D
ChEBI ID CHEBI:194124
Definition A triterpenoid saponin that is hederagenin attached to a α-L-arabinopyranosyl residue at position 3 via a glycosidic linkage and a 6-O-β-D-glucopyranosyl-β-D-glucopyranosyl residue at position 28 via an ester linkage. It is the active ingredient found in the traditional Chinese herb Radix Dipsaci.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Mark Williams
Supplier Information
Download Molfile XML SDF
Formula C47H76O18
Net Charge 0
Average Mass 929.107
Monoisotopic Mass 928.50317
InChI InChI=1S/C47H76O18/c1-42(2)13-15-47(41(59)65-40-37(58)34(55)32(53)26(63-40)20-61-38-36(57)33(54)31(52)25(18-48)62-38)16-14-45(5)22(23(47)17-42)7-8-28-43(3)11-10-29(64-39-35(56)30(51)24(50)19-60-39)44(4,21-49)27(43)9-12-46(28,45)6/h7,23-40,48-58H,8-21H2,1-6H3/t23-,24-,25+,26+,27+,28+,29-,30-,31+,32+,33-,34-,35+,36+,37+,38+,39-,40-,43-,44-,45+,46+,47-/m0/s1
InChIKey CCRXMHCQWYVXTE-HMRSNRLKSA-N
SMILES [H]C12CC(C)(C)CCC1(CCC1(C)C2=CCC2([H])C3(C)CCC(OC4OCC(O)C(O)C4O)C(C)(CO)C3([H])CCC12C)C(=O)OC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O
Metabolite of Species Details
Stauntonia hexaphylla (NCBI:txid41788) Found in leaf (BTO:0000713). See: PubMed
Stauntonia hexaphylla (NCBI:txid41788) Found in fruit (BTO:0000486). See: PubMed
Dipsacus asper (NCBI:txid516548) Found in Root (BTO:0001188). See: PubMed
Roles Classification
Biological Role(s): apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via saponin )
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
bone density conservation agent
An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
antilipemic drug
A substance used to treat hyperlipidemia (an excess of lipids in the blood).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing akebia saponin D (CHEBI:194124) has functional parent hederagenin (CHEBI:69579)
akebia saponin D (CHEBI:194124) has role anti-inflammatory agent (CHEBI:67079)
akebia saponin D (CHEBI:194124) has role antilipemic drug (CHEBI:35679)
akebia saponin D (CHEBI:194124) has role antineoplastic agent (CHEBI:35610)
akebia saponin D (CHEBI:194124) has role apoptosis inducer (CHEBI:68495)
akebia saponin D (CHEBI:194124) has role bone density conservation agent (CHEBI:50646)
akebia saponin D (CHEBI:194124) has role neuroprotective agent (CHEBI:63726)
akebia saponin D (CHEBI:194124) has role plant metabolite (CHEBI:76924)
akebia saponin D (CHEBI:194124) is a carboxylic ester (CHEBI:33308)
akebia saponin D (CHEBI:194124) is a pentacyclic triterpenoid (CHEBI:25872)
akebia saponin D (CHEBI:194124) is a trisaccharide derivative (CHEBI:63571)
akebia saponin D (CHEBI:194124) is a triterpenoid saponin (CHEBI:61778)
IUPAC Name
1-O-[3β-(α-L-arabinopyranosyloxy)-23-hydroxy-28-oxoolean-12-en-28-yl]-6-O-β-D-glucopyranosyl-β-D-glucopyranose
Synonyms Sources
3β-(α-L-arabinopyranosyloxy)-23-hydroxyoleana-12-ene-28-oic acid 6-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl ester ChEBI
ASA VI ChEBI
asperosaponin VI ChEBI
asperosaponin VI ChEBI
hederagenin 3-O-α-L-arabinopyranosyl-28-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside ChEBI
leiyemudanoside A ChEBI
tauroside St-G0-1 ChEBI
Registry Number Type Source
39524-08-8 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
19023535 PubMed citation Europe PMC
30092401 PubMed citation Europe PMC
30508505 PubMed citation Europe PMC
30808589 PubMed citation Europe PMC
30939835 PubMed citation Europe PMC
31193169 PubMed citation Europe PMC
31301930 PubMed citation Europe PMC
32323648 PubMed citation Europe PMC
32344355 PubMed citation Europe PMC
32488348 PubMed citation Europe PMC
33100875 PubMed citation Europe PMC
33241814 PubMed citation Europe PMC
33249542 PubMed citation Europe PMC
33446173 PubMed citation Europe PMC
33652261 PubMed citation Europe PMC
33935711 PubMed citation Europe PMC
34526673 PubMed citation Europe PMC
34901550 PubMed citation Europe PMC
35228043 PubMed citation Europe PMC
35310016 PubMed citation Europe PMC
35610721 PubMed citation Europe PMC
35783512 PubMed citation Europe PMC
36110522 PubMed citation Europe PMC
36234773 PubMed citation Europe PMC
36382134 PubMed citation Europe PMC
36471972 PubMed citation Europe PMC
36550906 PubMed citation Europe PMC
36595050 PubMed citation Europe PMC
Last Modified
13 January 2023