CHEBI:68603 - betamethasone phosphate

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name betamethasone phosphate
ChEBI ID CHEBI:68603
Definition A steroid phosphate that is the 21-O-phospho derivative of betamethasone.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C22H30FO8P
Net Charge 0
Average Mass 472.44100
Monoisotopic Mass 472.16623
InChI InChI=1S/C22H30FO8P/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30)/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
InChIKey VQODGRNSFPNSQE-DVTGEIKXSA-N
SMILES [H][C@@]12C[C@H](C)[C@](O)(C(=O)COP(O)(O)=O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
Roles Classification
Biological Role(s): immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing betamethasone phosphate (CHEBI:68603) has functional parent betamethasone (CHEBI:3077)
betamethasone phosphate (CHEBI:68603) has role anti-inflammatory agent (CHEBI:67079)
betamethasone phosphate (CHEBI:68603) has role immunosuppressive agent (CHEBI:35705)
betamethasone phosphate (CHEBI:68603) is a 11β-hydroxy steroid (CHEBI:35346)
betamethasone phosphate (CHEBI:68603) is a 17α-hydroxy steroid (CHEBI:35342)
betamethasone phosphate (CHEBI:68603) is a 20-oxo steroid (CHEBI:36885)
betamethasone phosphate (CHEBI:68603) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166)
betamethasone phosphate (CHEBI:68603) is a fluorinated steroid (CHEBI:50830)
betamethasone phosphate (CHEBI:68603) is a steroid phosphate (CHEBI:36944)
betamethasone phosphate (CHEBI:68603) is a tertiary α-hydroxy ketone (CHEBI:139592)
betamethasone phosphate (CHEBI:68603) is conjugate acid of betamethasone phosphate(2−) (CHEBI:68604)
Incoming betamethasone phosphate(2−) (CHEBI:68604) is conjugate base of betamethasone phosphate (CHEBI:68603)
IUPAC Name
(11β,16β)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl dihydrogen phosphate
Synonym Source
betamethasone 21-phosphate ChEBI
Manual Xref Database
4667 DrugCentral
View more database links
Citations Waiting for Citations Types Sources
15955367 PubMed citation Europe PMC
19244548 PubMed citation Europe PMC
19481700 PubMed citation Europe PMC
19525834 PubMed citation Europe PMC
19649162 PubMed citation Europe PMC
19716124 PubMed citation Europe PMC
19800603 PubMed citation Europe PMC
21178146 PubMed citation Europe PMC
21574866 PubMed citation Europe PMC
21855245 PubMed citation Europe PMC
21899210 PubMed citation Europe PMC
22154197 PubMed citation Europe PMC
23412914 PubMed citation Europe PMC
3547254 PubMed citation Europe PMC
9093018 PubMed citation Europe PMC
Last Modified
07 February 2018