CHEBI:91185 - ZM 323881

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ChEBI Name ZM 323881
ChEBI ID CHEBI:91185
Definition A member of the class of quinazolines carrying 2-fluoro-4-methyl-5-hydroxyanilino and benzyloxy substituents at positions 4 and 7 respectively.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C22H18FN3O2
Net Charge 0
Average Mass 375.396
Monoisotopic Mass 375.13830
InChI InChI=1S/C22H18FN3O2/c1-14-9-18(23)20(11-21(14)27)26-22-17-8-7-16(10-19(17)24-13-25-22)28-12-15-5-3-2-4-6-15/h2-11,13,27H,12H2,1H3,(H,24,25,26)
InChIKey NVBNDZZLJRYRPD-UHFFFAOYSA-N
SMILES C1(O)=C(C=C(C(=C1)NC=2N=CN=C3C2C=CC(=C3)OCC4=CC=CC=C4)F)C
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): vascular endothelial growth factor receptor antagonist
An antagonist at the vascular endothelial growth factor receptor.
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ChEBI Ontology
Outgoing ZM 323881 (CHEBI:91185) has role vascular endothelial growth factor receptor antagonist (CHEBI:65207)
ZM 323881 (CHEBI:91185) is a aromatic ether (CHEBI:35618)
ZM 323881 (CHEBI:91185) is a benzyl ether (CHEBI:59859)
ZM 323881 (CHEBI:91185) is a fluorophenol (CHEBI:142486)
ZM 323881 (CHEBI:91185) is a halophenol (CHEBI:38856)
ZM 323881 (CHEBI:91185) is a monofluorobenzenes (CHEBI:83575)
ZM 323881 (CHEBI:91185) is a organic cation (CHEBI:25697)
ZM 323881 (CHEBI:91185) is a quinazolines (CHEBI:38530)
ZM 323881 (CHEBI:91185) is a secondary amino compound (CHEBI:50995)
ZM 323881 (CHEBI:91185) is a substituted aniline (CHEBI:48975)
ZM 323881 (CHEBI:91185) is conjugate base of ZM 323881(1+) (CHEBI:91187)
Incoming ZM 323881(1+) (CHEBI:91187) is conjugate acid of ZM 323881 (CHEBI:91185)
IUPAC Name
5-{[7-(benzyloxy)quinazolin-4-yl]amino}-4-fluoro-2-methylphenol
Synonyms Sources
ZM-323881 ChEBI
ZM323881 ChEBI
Manual Xref Database
LSM-3513 LINCS
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Registry Number Type Source
13137893 Reaxys Registry Number Reaxys
Last Modified
01 November 2018