CHEBI:38666 - (R)-flurbiprofen

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name (R)-flurbiprofen
ChEBI ID CHEBI:38666
ChEBI ASCII Name (R)-flurbiprofen
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C15H13FO2
Net Charge 0
Average Mass 244.26092
Monoisotopic Mass 244.08996
InChI InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1
InChIKey SYTBZMRGLBWNTM-SNVBAGLBSA-N
SMILES C[C@@H](C(O)=O)c1ccc(c(F)c1)-c1ccccc1
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.
(via flurbiprofen )
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
(via flurbiprofen )
Application(s): antipyretic
A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
(via flurbiprofen )
non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
(via flurbiprofen )
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
(via flurbiprofen )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (R)-flurbiprofen (CHEBI:38666) is a flurbiprofen (CHEBI:5130)
(R)-flurbiprofen (CHEBI:38666) is enantiomer of (S)-flurbiprofen (CHEBI:42446)
Incoming (S)-flurbiprofen (CHEBI:42446) is enantiomer of (R)-flurbiprofen (CHEBI:38666)
IUPAC Name
(2R)-2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid
Synonyms Sources
(−)-(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid ChemIDplus
(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid ChEBI
(R)-2-fluoro-α-methyl(1,1'-biphenyl)-4-acetic acid ChemIDplus
Flurizan ChemIDplus
Tarenflurbil ChemIDplus
Registry Numbers Types Sources
4686157 Beilstein Registry Number Beilstein
51543-40-9 CAS Registry Number ChemIDplus
5745751 Beilstein Registry Number Beilstein
Last Modified
17 October 2009