CHEBI:84619 - (Sp)-8-bromo-cAMPS

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ChEBI Name (Sp)-8-bromo-cAMPS
ChEBI ID CHEBI:84619
ChEBI ASCII Name (Sp)-8-bromo-cAMPS
Definition A nucleoside 3',5'-cyclic phosphorothioate having 8-bromoadenine as the nucleobase (the Sp-stereoisomer).
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Margaret Duesbury
Supplier Information
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Formula C10H11BrN5O5PS
Net Charge 0
Average Mass 424.16800
Monoisotopic Mass 422.94019
InChI InChI=1S/C10H11BrN5O5PS/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(20-9)1-19-22(18,23)21-6/h2-3,5-6,9,17H,1H2,(H,18,23)(H2,12,13,14)/t3-,5-,6-,9-,22+/m1/s1
InChIKey RBORURQQJIQWBS-FHIGPPGSSA-N
SMILES Nc1ncnc2n([C@@H]3O[C@@H]4CO[P@@](S)(=O)O[C@H]4[C@H]3O)c(Br)nc12
Roles Classification
Biological Role(s): protein kinase agonist
An agonist that selectively binds to and activates a protein kinase receptor.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (Sp)-8-bromo-cAMPS (CHEBI:84619) has functional parent 3',5'-cyclic AMP (CHEBI:17489)
(Sp)-8-bromo-cAMPS (CHEBI:84619) has role protein kinase agonist (CHEBI:64106)
(Sp)-8-bromo-cAMPS (CHEBI:84619) is a nucleoside 3',5'-cyclic phosphorothioate (CHEBI:85287)
(Sp)-8-bromo-cAMPS (CHEBI:84619) is a organobromine compound (CHEBI:37141)
(Sp)-8-bromo-cAMPS (CHEBI:84619) is a purines (CHEBI:26401)
IUPAC Name
(2S,4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxy-2-sulfanyltetrahydro-2H,4H-2λ5-furo[3,2-d][1,3,2]dioxaphosphinin-2-one
Synonyms Sources
(Sp)-8-bromoadenosine-3',5'-cyclic monophosphorothioate ChEBI
8-bromo-Sp-cAMPS ChEBI
Sp-8-Br-cAMPS ChEBI
Registry Number Type Source
15036769 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
24605759 PubMed citation SUBMITTER
25274816 PubMed citation Europe PMC
Last Modified
23 March 2015