CHEBI:91182 - ZM 323881 hydrochloride

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ChEBI Name ZM 323881 hydrochloride
ChEBI ID CHEBI:91182
Definition A hydrochloride obtained by combining ZM 323881 with one molar equivalent of hydrochloric acid.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C22H19ClFN3O2
Net Charge 0
Average Mass 411.857
Monoisotopic Mass 411.11498
InChI InChI=1S/C22H18FN3O2.ClH/c1-14-9-18(23)20(11-21(14)27)26-22-17-8-7-16(10-19(17)24-13-25-22)28-12-15-5-3-2-4-6-15;/h2-11,13,27H,12H2,1H3,(H,24,25,26);1H
InChIKey AVRHWGLIYGJSOD-UHFFFAOYSA-N
SMILES C1(O)=C(C=C(C(=C1)NC=2N=CN=C3C2C=CC(=C3)OCC4=CC=CC=C4)F)C.Cl
Roles Classification
Biological Role(s): vascular endothelial growth factor receptor antagonist
An antagonist at the vascular endothelial growth factor receptor.
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing ZM 323881 hydrochloride (CHEBI:91182) has part ZM 323881(1+) (CHEBI:91187)
ZM 323881 hydrochloride (CHEBI:91182) has role EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor (CHEBI:62434)
ZM 323881 hydrochloride (CHEBI:91182) has role vascular endothelial growth factor receptor antagonist (CHEBI:65207)
ZM 323881 hydrochloride (CHEBI:91182) is a hydrochloride (CHEBI:36807)
IUPAC Names
5-{[7-(benzyloxy)quinazolin-4-yl]amino}-4-fluoro-2-methylphenol hydrochloride
7-(benzyloxy)-N-(2-fluoro-5-hydroxy-4-methylphenyl)quinazolin-4-aminium chloride
Synonyms Sources
ZM 323881 monohydrochloride ChEBI
ZM 323881.HCl ChEBI
ZM-323881 hydrochloride ChEBI
ZM-323881 monohydrochloride ChEBI
ZM-323881.HCl ChEBI
Registry Number Type Source
13172661 Reaxys Registry Number Reaxys
Last Modified
15 February 2016