BW B70C (CHEBI:75307)

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ChEBI Name	BW B70C

ChEBI ID	CHEBI:75307

Definition	A hydroxamic acid that is urea in which both the hydrogens attached to one of the nitrogens are replaced by a hydroxy and a (1E)-1-[3-(4-fluorophenoxy)phenyl]but-1-en-3-yl group. A selective inhibitor of arachidonate 5-lipoxygenase, it can be used for the treatment of asthma.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C17H17FN2O3

Net Charge

Average Mass

316.32690

Monoisotopic Mass

316.12232

InChI

InChI=1S/C17H17FN2O3/c1-12(20(22)17(19)21)5-6-13-3-2-4-16(11-13)23-15-9-7-14(18)8-10-15/h2-12,22H,1H3,(H2,19,21)/b6-5+

InChIKey

UAIYNMRLUHHRMF-AATRIKPKSA-N

SMILES

CC(\C=C\c1cccc(Oc2ccc(F)cc2)c1)N(O)C(N)=O

Roles Classification
Biological Role(s):	EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor A lipoxygenase inhibitor that interferes with the action of arachidonate 5-lipoxygenase (EC 1.13.11.34).

ChEBI Ontology
Outgoing	BW B70C (CHEBI:75307) has role EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor (CHEBI:64964) BW B70C (CHEBI:75307) is a aromatic ether (CHEBI:35618) BW B70C (CHEBI:75307) is a hydroxamic acid (CHEBI:24650) BW B70C (CHEBI:75307) is a organofluorine compound (CHEBI:37143) BW B70C (CHEBI:75307) is a ureas (CHEBI:47857)

IUPAC Name

1-{(3E)-4-[3-(4-fluorophenoxy)phenyl]but-3-en-2-yl}-1-hydroxyurea

Synonyms	Sources
(E)-N-(3-(3-(4-Fluorophenoxy)phenyl)-1-(R,S)-methylprop-2-enyl)-N-hydroxyurea	ChEBI
70C	ChemIDplus
BW-B70C	ChEBI

Last Modified

23 August 2013