CHEBI:73303 - aminopotentidine

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ChEBI Name aminopotentidine
ChEBI ID CHEBI:73303
Definition A benzamide obtained by formal condensation of the carboxy group of 4-aminobenzoic acid with the primary amino group of 1-(2-aminoethyl)-2-cyano-3-{3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}guanidine.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Margaret Duesbury
Supplier Information
Download Molfile XML SDF
Formula C26H35N7O2
Net Charge 0
Average Mass 477.60180
Monoisotopic Mass 477.28522
InChI InChI=1S/C26H35N7O2/c27-20-32-26(31-14-13-29-25(34)22-8-10-23(28)11-9-22)30-12-5-17-35-24-7-4-6-21(18-24)19-33-15-2-1-3-16-33/h4,6-11,18H,1-3,5,12-17,19,28H2,(H,29,34)(H2,30,31,32)
InChIKey CICDSYWWNDGAGD-UHFFFAOYSA-N
SMILES Nc1ccc(cc1)C(=O)NCCN\C(NCCCOc1cccc(CN2CCCCC2)c1)=N\C#N
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): H2-receptor antagonist
H2-receptor antagonists are the drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of endogenous histamine.
Application(s): H2-receptor antagonist
H2-receptor antagonists are the drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of endogenous histamine.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing aminopotentidine (CHEBI:73303) has role H2-receptor antagonist (CHEBI:37961)
aminopotentidine (CHEBI:73303) is a aromatic ether (CHEBI:35618)
aminopotentidine (CHEBI:73303) is a benzamides (CHEBI:22702)
aminopotentidine (CHEBI:73303) is a guanidines (CHEBI:24436)
aminopotentidine (CHEBI:73303) is a nitrile (CHEBI:18379)
aminopotentidine (CHEBI:73303) is a piperidines (CHEBI:26151)
aminopotentidine (CHEBI:73303) is a substituted aniline (CHEBI:48975)
IUPAC Name
4-amino-N-[2-(N''-cyano-N'-{3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}carbamimidamido)ethyl]benzamide
Registry Number Type Source
5487725 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
12065605 PubMed citation Europe PMC
20509312 PubMed citation Europe PMC
23597562 PubMed citation Europe PMC
Last Modified
29 April 2013